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      <journal-id journal-id-type="publisher">JOHS</journal-id>
      <journal-id journal-id-type="nlm-ta">Journ of Health Scien</journal-id>
        <journal-title>Journal of HealthCare Sciences</journal-title>
        <abbrev-journal-title abbrev-type="pubmed">Journ of Health Scien</abbrev-journal-title>
      <issn pub-type="ppub">2231-2196</issn>
      <issn pub-type="opub">0975-5241</issn>
        <publisher-name>Radiance Research Academy</publisher-name>
      <article-id pub-id-type="publisher-id">43</article-id>
      <article-id pub-id-type="doi">http://dx.doi.org/10.52533/JOHS.2021.1902</article-id>
      <article-id pub-id-type="doi-url"/>
        <subj-group subj-group-type="heading">
        <article-title>Negative Appendectomy after Histopathology: Results, Rates, and Predictive Factors&#13;
        <contrib contrib-type="author">
            <given-names>Sultan H.</given-names>
        <contrib contrib-type="author">
            <given-names>Aishah S.</given-names>
        <contrib contrib-type="author">
            <given-names>Shahad S.</given-names>
        <contrib contrib-type="author">
            <given-names>Ebtesam A.</given-names>
        <contrib contrib-type="author">
            <given-names>Ghayda S.</given-names>
        <contrib contrib-type="author">
            <given-names>Hind K.</given-names>
        <contrib contrib-type="author">
            <given-names>Asma A.</given-names>
      <pub-date pub-type="ppub">
        <copyright-statement>This article is copyright of Popeye Publishing, 2009</copyright-statement>
        <license license-type="open-access" href="http://creativecommons.org/licenses/by/4.0/">
          <license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.</license-p>
        <p>Background: Appendicitis is one of the most common causes of acute abdomen caused by an inflammation of the lining of the vermiform appendix. The management is usually emergent surgical removal.  Histopathological examination of the appendectomy specimens are routinely carried out to correlate the histological findings of appendectomy specimens with the clinical diagnosis of acute appendicitis.&#13;
Methods: This is a retrospective chart review study that utilized the medical records of patients who underwent appendectomy from January 1, 2016 to March 31, 2019 in King Fahad Specialist Hospital (KFSH) in Buraidah.&#13;
Results: Negative Appendectomy (NA) rate in our study was 7.2% of total 488 patient. According to our findings, a positive computed tomography (CT) was the sole independent predictor of the absence of NA. The prevalence of NA increased among patients with negative CT, an Alvarado score ? 4 and those with an illness duration &gt;1 day.&#13;
Conclusions: Appendicitis can be challenging to diagnose, and misdiagnosis was mostly associated with female gender. To reduce NA rate, CT scans can be used for patients with symptoms of acute appendicitis and the improvement of the Alvarado score. Further prospective studies are needed to validate our findings and demonstrate how unnecessary appendectomies can be avoided.&#13;
        <kwd>Negative appendectomy</kwd>
        <kwd> acute appendicitis</kwd>
        <kwd> Alvarado score</kwd>