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<article xlink="http://www.w3.org/1999/xlink" dtd-version="1.0" article-type="orthopaedics" lang="en">
  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher">JOHS</journal-id>
      <journal-id journal-id-type="nlm-ta">Journ of Health Scien</journal-id>
      <journal-title-group>
        <journal-title>Journal of HealthCare Sciences</journal-title>
        <abbrev-journal-title abbrev-type="pubmed">Journ of Health Scien</abbrev-journal-title>
      </journal-title-group>
      <issn pub-type="ppub">2231-2196</issn>
      <issn pub-type="opub">0975-5241</issn>
      <publisher>
        <publisher-name>Radiance Research Academy</publisher-name>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">396</article-id>
      <article-id pub-id-type="doi">http://dx.doi.org/10.52533/JOHS.2025.50401</article-id>
      <article-id pub-id-type="doi-url"/>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Orthopaedics</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Ultrastructure Study of Anterior Cruciate Ligament of Advanced Osteoarthritis Patient Subjected to Total Knee Replacement Surgery&#13;
</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <name>
            <surname>Hegaze</surname>
            <given-names>Adel</given-names>
          </name>
        </contrib>
      </contrib-group>
      <pub-date pub-type="ppub">
        <day>20</day>
        <month>04</month>
        <year>2025</year>
      </pub-date>
      <volume>5</volume>
      <issue>4</issue>
      <fpage>121</fpage>
      <lpage>130</lpage>
      <permissions>
        <copyright-statement>This article is copyright of Popeye Publishing, 2009</copyright-statement>
        <copyright-year>2009</copyright-year>
        <license license-type="open-access" href="http://creativecommons.org/licenses/by/4.0/">
          <license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.</license-p>
        </license>
      </permissions>
      <abstract>
        <p>Background: The Anterior Cruciate ligament (ACL) has the highest percentage of elastic fibers. It is one of the most common affected ligaments in sport injuries. Osteoarthritic patients often present to the clinic with painful ACL.&#13;
&#13;
Case Reports: ACLs were collected from two patient and a total of four knees. The composition of ligament as regard the collagen fibrils, collagen organization, density of fibroblasts and blood vessels, and distribution of the collagen type I, III and V fibrils were examined.&#13;
&#13;
Results: The ultrastructural cellular features of the tibial stump of the ruptured ACL showed the presence of myofibroblasts.&#13;
&#13;
Conclusion: The finding has a potential bearing on the healing capacity of the ruptured stump and on the functional outcome of the remnant-preserving ACL reconstruction. In addition, the fibril diameter range and collagen fibril index were similar to the previous studies despite of the age effect.&#13;
</p>
      </abstract>
      <kwd-group>
        <kwd>ACL</kwd>
        <kwd> collagen fibril</kwd>
        <kwd> ultrastructure</kwd>
        <kwd> knee OA</kwd>
        <kwd> microscopic examination</kwd>
      </kwd-group>
    </article-meta>
  </front>
</article>