<?xml version="1.0" encoding="UTF-8" standalone="yes"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.2d1 20170631//EN" "JATS-journalpublishing1.dtd">
<article xlink="http://www.w3.org/1999/xlink" dtd-version="1.0" article-type="dentistry" lang="en">
<front>
<journal-meta>
<journal-id journal-id-type="publisher">JOHS</journal-id>
<journal-id journal-id-type="nlm-ta">Journ of Health Scien</journal-id>
<journal-title-group>
<journal-title>Journal of HealthCare Sciences</journal-title>
<abbrev-journal-title abbrev-type="pubmed">Journ of Health Scien</abbrev-journal-title>
</journal-title-group>
<issn pub-type="ppub">2231-2196</issn>
<issn pub-type="opub">0975-5241</issn>
<publisher>
<publisher-name>Radiance Research Academy</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="publisher-id">390</article-id>
<article-id pub-id-type="doi">http://dx.doi.org/10.52533/JOHS.2025.50109</article-id>
<article-id pub-id-type="doi-url"/>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Dentistry</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Assessing the Role of Calcium Silicate-Based Sealers in Reducing Post-Treatment Microleakage
</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname>Abdulwahab</surname>
<given-names>Maha Ali</given-names>
</name>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Thobaiti</surname>
<given-names>Ibrahim Dhaifallah Al</given-names>
</name>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Alqarni</surname>
<given-names>Abdulaziz Abdulrahman</given-names>
</name>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Alharbi</surname>
<given-names>Ayman Thamer</given-names>
</name>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Siddiq</surname>
<given-names>Abubakr Ahmed</given-names>
</name>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Alansari</surname>
<given-names>Juwana Khalid</given-names>
</name>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Alnashmi</surname>
<given-names>Fadhel Hejji</given-names>
</name>
</contrib>
</contrib-group>
<pub-date pub-type="ppub">
<day>24</day>
<month>01</month>
<year>2025</year>
</pub-date>
<volume>5</volume>
<issue>1</issue>
<fpage>69</fpage>
<lpage>76</lpage>
<permissions>
<copyright-statement>This article is copyright of Popeye Publishing, 2009</copyright-statement>
<copyright-year>2009</copyright-year>
<license license-type="open-access" href="http://creativecommons.org/licenses/by/4.0/">
<license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.</license-p>
</license>
</permissions>
<abstract>
<p>Calcium silicate-based sealers have emerged as a transformative innovation in endodontics, offering solutions to long-standing challenges such as microleakage, biocompatibility, and durability. These sealers demonstrate exceptional adaptability due to their hydraulic setting properties, ensuring tight seals in moist environments and reducing micro-gaps commonly associated with traditional materials. Their bioactivity, characterized by the release of calcium ions and hydroxyapatite formation, promotes periapical tissue healing and enhances the interface between dentin and the sealer, contributing to long-term treatment success. High alkalinity during setting provides sustained antimicrobial activity, effectively inhibiting bacterial proliferation within the root canal system. This property, coupled with low solubility and resistance to degradation, ensures stability and reliability even under challenging clinical conditions. Comparative studies reveal that calcium silicate-based sealers outperform traditional alternatives, such as epoxy resin and zinc oxide-eugenol sealers, in key performance metrics, including sealing ability, biocompatibility, and post-treatment outcomes. Clinically, these sealers are compatible with various obturation techniques, simplifying application while maintaining efficacy in sealing complex canal anatomies. Patients treated with calcium silicate-based sealers report lower incidences of postoperative pain, attributed to their anti-inflammatory properties and enhanced healing potential. Emerging research continues to refine their formulations, addressing limitations like prolonged setting times and optimizing handling properties. The integration of calcium silicate-based sealers into routine endodontic practice signifies a paradigm shift, driven by their ability to improve clinical outcomes and reduce failure rates. As material advancements progress, these sealers hold promises for broader applications in complex cases, further enhancing the predictability and success of root canal treatments. Their superior performance establishes them as a cornerstone in modern endodontic care, addressing both current and future challenges in the field.
</p>
</abstract>
<kwd-group>
<kwd>Calcium silicate sealers</kwd>
<kwd> microleakage prevention</kwd>
<kwd> endodontic treatment</kwd>
<kwd> bioactive materials</kwd>
<kwd> root canal sealers</kwd>
</kwd-group>
</article-meta>
</front>
</article>