<?xml version="1.0" encoding="UTF-8" standalone="yes"?> <!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.2d1 20170631//EN" "JATS-journalpublishing1.dtd"> <article xlink="http://www.w3.org/1999/xlink" dtd-version="1.0" article-type="pharmaceutical-science" lang="en"> <front> <journal-meta> <journal-id journal-id-type="publisher">JOHS</journal-id> <journal-id journal-id-type="nlm-ta">Journ of Health Scien</journal-id> <journal-title-group> <journal-title>Journal of HealthCare Sciences</journal-title> <abbrev-journal-title abbrev-type="pubmed">Journ of Health Scien</abbrev-journal-title> </journal-title-group> <issn pub-type="ppub">2231-2196</issn> <issn pub-type="opub">0975-5241</issn> <publisher> <publisher-name>Radiance Research Academy</publisher-name> </publisher> </journal-meta> <article-meta> <article-id pub-id-type="publisher-id">377</article-id> <article-id pub-id-type="doi">http://dx.doi.org/10.52533/JOHS.2024.41256</article-id> <article-id pub-id-type="doi-url"/> <article-categories> <subj-group subj-group-type="heading"> <subject>Pharmaceutical Science</subject> </subj-group> </article-categories> <title-group> <article-title>Strategies for Managing Medication Compliance in Complex Chronic Conditions </article-title> </title-group> <contrib-group> <contrib contrib-type="author"> <name> <surname>Albishi</surname> <given-names>Bandari Saad</given-names> </name> </contrib> <contrib contrib-type="author"> <name> <surname>Baraja</surname> <given-names>Mervat Abdullah</given-names> </name> </contrib> <contrib contrib-type="author"> <name> <surname>Amashah</surname> <given-names>Adel Eabdalrahim</given-names> </name> </contrib> <contrib contrib-type="author"> <name> <surname>Alzahrani</surname> <given-names>Bandar Mohammed</given-names> </name> </contrib> <contrib contrib-type="author"> <name> <surname>Alshaeri</surname> <given-names>Afnan Mohammad</given-names> </name> </contrib> </contrib-group> <pub-date pub-type="ppub"> <day>31</day> <month>12</month> <year>2024</year> </pub-date> <volume>4</volume> <issue>12</issue> <fpage>1057</fpage> <lpage>1063</lpage> <permissions> <copyright-statement>This article is copyright of Popeye Publishing, 2009</copyright-statement> <copyright-year>2009</copyright-year> <license license-type="open-access" href="http://creativecommons.org/licenses/by/4.0/"> <license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.</license-p> </license> </permissions> <abstract> <p>Medication adherence is a crucial determinant of therapeutic success, particularly in managing chronic conditions that require long-term, often complex, treatment regimens. Despite its importance, adherence remains a significant challenge globally, with non-compliance rates ranging from 30% to 50%, leading to disease progression and increased healthcare costs. Addressing these challenges necessitates multifaceted approaches that integrate behavioral, technological, and collaborative strategies. Behavioral interventions, including motivational interviewing and cognitive-behavioral therapy, focus on modifying patient attitudes and behaviors toward medication. These approaches align treatment goals with patient values, enhancing engagement and adherence. Simultaneously, technological innovations such as mobile health applications, smart pill dispensers, and biosensors provide real-time monitoring and support, empowering patients while enabling timely healthcare provider interventions. Collaborative care models and multidisciplinary approaches play a critical role by leveraging the expertise of various healthcare professionals, including physicians, pharmacists, and behavioral health specialists. These frameworks ensure a holistic focus on patient needs, addressing barriers such as regimen complexity, psychosocial challenges, and financial constraints. Furthermore, the integration of community health workers and the use of shared electronic health records facilitate coordinated care and better outcomes. Patient education remains a cornerstone across all strategies, ensuring individuals understand their conditions and treatment regimens. This foundational element enhances self-management and long-term adherence. Technological advancements, coupled with data-driven analytics, augment these efforts by providing actionable insights into patient behaviors and enabling proactive interventions. Through a combination of patient-centered care, innovative technologies, and collaborative efforts, these strategies aim to overcome the multifactorial barriers to medication adherence. Such integrative approaches are essential to improving outcomes, reducing healthcare costs, and enhancing the quality of life for individuals managing chronic conditions. These advancements pave the way for sustainable and effective solutions to one of healthcare’s most persistent challenges. </p> </abstract> <kwd-group> <kwd>Medication adherence</kwd> <kwd> chronic conditions</kwd> <kwd> behavioral interventions</kwd> <kwd> technological innovations</kwd> <kwd> collaborative care models</kwd> </kwd-group> </article-meta> </front> </article>