<?xml version="1.0" encoding="UTF-8" standalone="yes"?> <!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.2d1 20170631//EN" "JATS-journalpublishing1.dtd"> <article xlink="http://www.w3.org/1999/xlink" dtd-version="1.0" article-type="surgery" lang="en"> <front> <journal-meta> <journal-id journal-id-type="publisher">JOHS</journal-id> <journal-id journal-id-type="nlm-ta">Journ of Health Scien</journal-id> <journal-title-group> <journal-title>Journal of HealthCare Sciences</journal-title> <abbrev-journal-title abbrev-type="pubmed">Journ of Health Scien</abbrev-journal-title> </journal-title-group> <issn pub-type="ppub">2231-2196</issn> <issn pub-type="opub">0975-5241</issn> <publisher> <publisher-name>Radiance Research Academy</publisher-name> </publisher> </journal-meta> <article-meta> <article-id pub-id-type="publisher-id">335</article-id> <article-id pub-id-type="doi">http://dx.doi.org/10.52533/JOHS.2024.41214</article-id> <article-id pub-id-type="doi-url"/> <article-categories> <subj-group subj-group-type="heading"> <subject>Surgery</subject> </subj-group> </article-categories> <title-group> <article-title>A Rare Case of Gastrointestinal Basidiobolomycosis Mimicking Appendicitis in a Young Adult </article-title> </title-group> <contrib-group> <contrib contrib-type="author"> <name> <surname>Barnawi</surname> <given-names>Zahrah</given-names> </name> </contrib> <contrib contrib-type="author"> <name> <surname>Alharthi</surname> <given-names>Abdulrahman</given-names> </name> </contrib> <contrib contrib-type="author"> <name> <surname>Alhassani</surname> <given-names>Abdulrahman</given-names> </name> </contrib> <contrib contrib-type="author"> <name> <surname>Qamrah</surname> <given-names>Wied</given-names> </name> </contrib> <contrib contrib-type="author"> <name> <surname>Almasoudi</surname> <given-names>Arif</given-names> </name> </contrib> <contrib contrib-type="author"> <name> <surname>Laswad</surname> <given-names>Bassam Bin</given-names> </name> </contrib> <contrib contrib-type="author"> <name> <surname>Alasiri</surname> <given-names>Alaa</given-names> </name> </contrib> </contrib-group> <pub-date pub-type="ppub"> <day>16</day> <month>12</month> <year>2024</year> </pub-date> <volume>4</volume> <issue>12</issue> <fpage>736</fpage> <lpage>743</lpage> <permissions> <copyright-statement>This article is copyright of Popeye Publishing, 2009</copyright-statement> <copyright-year>2009</copyright-year> <license license-type="open-access" href="http://creativecommons.org/licenses/by/4.0/"> <license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.</license-p> </license> </permissions> <abstract> <p>Background: Gastrointestinal basidiobolomycosis (GIB) is a rare fungal infection caused by Basidiobolus ranarum, primarily affecting immunocompetent individuals in tropical and subtropical regions. It mimics common abdominal conditions, such as appendicitis and malignancies, leading to diagnostic challenges. Diagnosis relies on histopathology, and treatment involves a combination of surgical resection and antifungal therapy. Case presentation: A 17-year-old male presented with right lower quadrant pain and a pelvic mass initially suspected to be an appendicular abscess. Initial diagnosis suggested a perforated appendix. After unsuccessful conservative management, open appendectomy revealed GIB on histopathology. The patient received itraconazole for 9 months, resulting in significant clinical improvement and reduction in mass size, as confirmed by follow-up imaging. Conclusion: This case highlights the diagnostic challenges of GIB, particularly in regions where it is endemic, and the importance of considering it in the differential diagnosis of atypical abdominal presentations. Histopathology remains critical for accurate diagnosis, and a combined approach of surgical intervention and prolonged antifungal therapy proved effective, with close follow-up essential to monitor treatment response and prevent recurrence. The case underscores the need for increased awareness among clinicians to facilitate timely diagnosis and management of this rare condition. </p> </abstract> <kwd-group> <kwd>Gastrointestinal basidiobolomycosis</kwd> <kwd> Appendectomy</kwd> <kwd> Fungal infection</kwd> <kwd> Case report</kwd> </kwd-group> </article-meta> </front> </article>