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<article xlink="http://www.w3.org/1999/xlink" dtd-version="1.0" article-type="dentistry" lang="en">
  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher">JOHS</journal-id>
      <journal-id journal-id-type="nlm-ta">Journ of Health Scien</journal-id>
      <journal-title-group>
        <journal-title>Journal of HealthCare Sciences</journal-title>
        <abbrev-journal-title abbrev-type="pubmed">Journ of Health Scien</abbrev-journal-title>
      </journal-title-group>
      <issn pub-type="ppub">2231-2196</issn>
      <issn pub-type="opub">0975-5241</issn>
      <publisher>
        <publisher-name>Radiance Research Academy</publisher-name>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">333</article-id>
      <article-id pub-id-type="doi">http://dx.doi.org/10.52533/JOHS.2024.41212</article-id>
      <article-id pub-id-type="doi-url"/>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Dentistry</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Clinical Applications of Mineral Trioxide Aggregate in Dental Procedures&#13;
</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <name>
            <surname>Alshargawi</surname>
            <given-names>Waleed Khalid</given-names>
          </name>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Alomari</surname>
            <given-names>Abeer Abdulaziz</given-names>
          </name>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Alharbi</surname>
            <given-names>Ali Obaid</given-names>
          </name>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Alhowimel</surname>
            <given-names>Sliman Mohamad</given-names>
          </name>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Alawbthani</surname>
            <given-names>Muhannad Waleed</given-names>
          </name>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Alasiri</surname>
            <given-names>Lujain Qassim</given-names>
          </name>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Alreshaid</surname>
            <given-names>Ahmed Abdulrahman</given-names>
          </name>
        </contrib>
      </contrib-group>
      <pub-date pub-type="ppub">
        <day>8</day>
        <month>12</month>
        <year>2024</year>
      </pub-date>
      <volume>4</volume>
      <issue>12</issue>
      <fpage>721</fpage>
      <lpage>728</lpage>
      <permissions>
        <copyright-statement>This article is copyright of Popeye Publishing, 2009</copyright-statement>
        <copyright-year>2009</copyright-year>
        <license license-type="open-access" href="http://creativecommons.org/licenses/by/4.0/">
          <license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.</license-p>
        </license>
      </permissions>
      <abstract>
        <p>Mineral Trioxide Aggregate (MTA) is a widely utilized material in modern dentistry, known for its exceptional biocompatibility, bioactivity, and versatility. Initially developed for root-end filling, its applications have expanded to include pulp therapy, root canal sealing, perforation repair, and regenerative endodontics. MTA’s bioactivity is attributed to its ability to release calcium ions upon hydration, promoting hydroxyapatite formation and creating an environment conducive to tissue regeneration. These properties, coupled with its excellent sealing ability and antibacterial activity, make it a reliable choice for challenging clinical scenarios. In pulp therapy, MTA has demonstrated superior outcomes in direct pulp capping and apexogenesis, ensuring the preservation of pulp vitality and promoting dentinal bridge formation. Its role in root canal sealing and repair is equally significant, with studies confirming its effectiveness in achieving a tight seal and minimizing bacterial infiltration. MTA’s bioactive and biocompatible nature also enhances its success in repairing perforations and managing resorptive defects, where it supports the regeneration of surrounding tissues and stabilizes the tooth structure. In regenerative endodontics, MTA plays a pivotal role in pulp revitalization and the treatment of necrotic immature teeth. Its ability to foster revascularization and support tissue growth bridges traditional endodontics and tissue engineering. Despite its advantages, challenges such as prolonged setting time, handling difficulties, and cost remain. However, advancements in formulation and technique have mitigated these limitations, expanding its clinical utility. The effectiveness of MTA across diverse applications underscores its significance in advancing dental care. Its unique properties not only improve treatment outcomes but also offer innovative solutions for preserving natural dentition. As research continues to refine its applications and address existing limitations, MTA is poised to remain a cornerstone material in modern dentistry.&#13;
</p>
      </abstract>
      <kwd-group>
        <kwd>Mineral Trioxide Aggregate</kwd>
        <kwd> bioactivity</kwd>
        <kwd> pulp therapy</kwd>
        <kwd> regenerative endodontics</kwd>
        <kwd> perforation repair</kwd>
      </kwd-group>
    </article-meta>
  </front>
</article>