<?xml version="1.0" encoding="UTF-8" standalone="yes"?> <!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.2d1 20170631//EN" "JATS-journalpublishing1.dtd"> <article xlink="http://www.w3.org/1999/xlink" dtd-version="1.0" article-type="dentistry" lang="en"> <front> <journal-meta> <journal-id journal-id-type="publisher">JOHS</journal-id> <journal-id journal-id-type="nlm-ta">Journ of Health Scien</journal-id> <journal-title-group> <journal-title>Journal of HealthCare Sciences</journal-title> <abbrev-journal-title abbrev-type="pubmed">Journ of Health Scien</abbrev-journal-title> </journal-title-group> <issn pub-type="ppub">2231-2196</issn> <issn pub-type="opub">0975-5241</issn> <publisher> <publisher-name>Radiance Research Academy</publisher-name> </publisher> </journal-meta> <article-meta> <article-id pub-id-type="publisher-id">320</article-id> <article-id pub-id-type="doi">http://dx.doi.org/10.52533/JOHS.2024.41110</article-id> <article-id pub-id-type="doi-url"/> <article-categories> <subj-group subj-group-type="heading"> <subject>Dentistry</subject> </subj-group> </article-categories> <title-group> <article-title>Prognostic Factors in Determining Success and Failure Rates in Endodontics </article-title> </title-group> <contrib-group> <contrib contrib-type="author"> <name> <surname>Alkaoud</surname> <given-names>Reem Ali</given-names> </name> </contrib> <contrib contrib-type="author"> <name> <surname>Mohammed</surname> <given-names>Yahya Hady</given-names> </name> </contrib> <contrib contrib-type="author"> <name> <surname>Galilah</surname> <given-names>Amal Ali</given-names> </name> </contrib> <contrib contrib-type="author"> <name> <surname>Alghamdi</surname> <given-names>Fatmah Saad</given-names> </name> </contrib> <contrib contrib-type="author"> <name> <surname>Alhabashi</surname> <given-names>Nahed Abdullah</given-names> </name> </contrib> </contrib-group> <pub-date pub-type="ppub"> <day>25</day> <month>11</month> <year>2024</year> </pub-date> <volume>4</volume> <issue>11</issue> <fpage>622</fpage> <lpage>629</lpage> <permissions> <copyright-statement>This article is copyright of Popeye Publishing, 2009</copyright-statement> <copyright-year>2009</copyright-year> <license license-type="open-access" href="http://creativecommons.org/licenses/by/4.0/"> <license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.</license-p> </license> </permissions> <abstract> <p>Endodontic treatment success depends on a complex interplay of anatomical, microbial, patient-related, and procedural factors. Variations in root canal anatomy, such as apical deltas, accessory canals, and isthmuses, can harbor bacteria despite advanced cleaning techniques, contributing to reinfection and treatment failure. The use of modern imaging technologies and precision tools like rotary instrumentation improves canal visualization and accessibility, while innovative irrigation techniques and adjuncts enhance microbial control, addressing limitations of conventional methods. Microbial factors, particularly the persistence of biofilm-forming bacteria such as Enterococcus faecalis, challenge complete disinfection. These resilient species can survive intracanal treatments, necessitating a multi-modal approach combining antimicrobial agents and advanced activation techniques to disrupt biofilms. Patient-specific variables, including systemic health conditions, immune status, and age, further impact endodontic outcomes by influencing healing capacities and susceptibility to reinfection. Diabetic patients, for example, face delayed healing, increasing the likelihood of complications. The long-term success of endodontically treated teeth also relies heavily on post-treatment restoration. A well-sealed, full-coverage restoration prevents microbial infiltration and protects the tooth from fractures under occlusal load. Adhesive materials and fiber posts provide added reinforcement, especially for teeth with substantial coronal damage, and help distribute functional forces evenly. Timely and durable restorations contribute significantly to the survival of treated teeth, with immediate or early definitive restorations showing improved outcomes. Effective endodontic care requires a comprehensive understanding of these prognostic factors, emphasizing personalized treatment strategies to improve success rates. Advances in procedural techniques, restorative materials, and an in-depth appreciation of patient-related variables collectively contribute to enhanced endodontic outcomes, reducing failure rates and increasing long-term tooth preservation. </p> </abstract> <kwd-group> <kwd>Endodontics</kwd> <kwd> failure rates</kwd> <kwd> success rates</kwd> </kwd-group> </article-meta> </front> </article>