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<article xlink="http://www.w3.org/1999/xlink" dtd-version="1.0" article-type="pediatrics" lang="en">
  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher">JOHS</journal-id>
      <journal-id journal-id-type="nlm-ta">Journ of Health Scien</journal-id>
      <journal-title-group>
        <journal-title>Journal of HealthCare Sciences</journal-title>
        <abbrev-journal-title abbrev-type="pubmed">Journ of Health Scien</abbrev-journal-title>
      </journal-title-group>
      <issn pub-type="ppub">2231-2196</issn>
      <issn pub-type="opub">0975-5241</issn>
      <publisher>
        <publisher-name>Radiance Research Academy</publisher-name>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">258</article-id>
      <article-id pub-id-type="doi">http://dx.doi.org/10.52533/JOHS.2024.40109</article-id>
      <article-id pub-id-type="doi-url"/>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Pediatrics</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Etiology, Pathophysiology, Diagnosis and Management of Kawasaki Disease&#13;
</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <name>
            <surname>Alzamzami</surname>
            <given-names>Abdulghani</given-names>
          </name>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Almuqaytib</surname>
            <given-names>Osama</given-names>
          </name>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Alsaadi</surname>
            <given-names>Ahmad</given-names>
          </name>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Alasmari</surname>
            <given-names>Ahmed</given-names>
          </name>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Alsuwat</surname>
            <given-names>Khalid</given-names>
          </name>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Abdullah</surname>
            <given-names>Ahmed Al</given-names>
          </name>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Alomair</surname>
            <given-names>Abdulaziz</given-names>
          </name>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Alomair</surname>
            <given-names>Asalah</given-names>
          </name>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Alawami</surname>
            <given-names>Noor</given-names>
          </name>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Alamodi</surname>
            <given-names>Anas</given-names>
          </name>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Alismail</surname>
            <given-names>Abdullah</given-names>
          </name>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Alenezi</surname>
            <given-names>Bandar</given-names>
          </name>
        </contrib>
      </contrib-group>
      <pub-date pub-type="ppub">
        <day>13</day>
        <month>01</month>
        <year>2024</year>
      </pub-date>
      <volume>4</volume>
      <issue>1	</issue>
      <fpage>71</fpage>
      <lpage>76</lpage>
      <permissions>
        <copyright-statement>This article is copyright of Popeye Publishing, 2009</copyright-statement>
        <copyright-year>2009</copyright-year>
        <license license-type="open-access" href="http://creativecommons.org/licenses/by/4.0/">
          <license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.</license-p>
        </license>
      </permissions>
      <abstract>
        <p>Kawasaki Disease (KD) has been a challenge in medicine ever since it was first described in 1967. This illness presents as a fever accompanied by a range of mucocutaneous symptoms making it crucial to have sharp diagnostic skills. It is characterized by inflammation of arteries throughout the body particularly affecting the cardiovascular system. Suspected triggers include agents, genetic factors and immune responses. KD pathophysiology is closely linked to dysregulation, especially involving inflammatory cytokines. Diagnosis relies on criteria such as fever for more than five days and specific symptoms. The primary pharmacological treatments involve immunoglobulin (IVIG) and aspirin to reduce inflammation and prevent complications in the arteries. In cases corticosteroids and immunomodulatory agents may be considered. Long term follow-up with collaboration among healthcare professionals is essential for monitoring any abnormalities in the arteries. Echocardiography plays a role in this process by providing insights into complications that may arise over time. Ongoing research aims to explore options as part of a comprehensive approach to KD management that emphasizes continuous research and an adaptable strategy for achieving the best possible outcomes.&#13;
</p>
      </abstract>
      <kwd-group>
        <kwd>Kawasaki Disease</kwd>
        <kwd> Pediatric Vasculitis</kwd>
        <kwd> Immune Dysregulation</kwd>
        <kwd> Coronary Artery Abnormalities</kwd>
        <kwd> Intravenous Immunoglobulin</kwd>
      </kwd-group>
    </article-meta>
  </front>
</article>