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<article xlink="http://www.w3.org/1999/xlink" dtd-version="1.0" article-type="dentistry" lang="en">
  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher">JOHS</journal-id>
      <journal-id journal-id-type="nlm-ta">Journ of Health Scien</journal-id>
      <journal-title-group>
        <journal-title>Journal of HealthCare Sciences</journal-title>
        <abbrev-journal-title abbrev-type="pubmed">Journ of Health Scien</abbrev-journal-title>
      </journal-title-group>
      <issn pub-type="ppub">2231-2196</issn>
      <issn pub-type="opub">0975-5241</issn>
      <publisher>
        <publisher-name>Radiance Research Academy</publisher-name>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">246</article-id>
      <article-id pub-id-type="doi">http://dx.doi.org/10.52533/JOHS.2023.31230</article-id>
      <article-id pub-id-type="doi-url"/>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Dentistry</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>The Impact of Systemic Diseases on Endodontic Treatment Outcomes&#13;
</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <name>
            <surname>Qasim</surname>
            <given-names>Abrar</given-names>
          </name>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Al-Hajji</surname>
            <given-names>Zuhair</given-names>
          </name>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Almutairy</surname>
            <given-names>Yasser</given-names>
          </name>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Shahrkhani</surname>
            <given-names>Abdulmalik</given-names>
          </name>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Eid</surname>
            <given-names>Fatimah Al</given-names>
          </name>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Hawsawi</surname>
            <given-names>Marwan</given-names>
          </name>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Aljishi</surname>
            <given-names>Reem</given-names>
          </name>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Alzahrani</surname>
            <given-names>Meshal</given-names>
          </name>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Alnassaralhassn</surname>
            <given-names>Huda</given-names>
          </name>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Al-Fadhel</surname>
            <given-names>Naif</given-names>
          </name>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Ahmed</surname>
            <given-names>Bayan</given-names>
          </name>
        </contrib>
      </contrib-group>
      <pub-date pub-type="ppub">
        <day>28</day>
        <month>12</month>
        <year>2023</year>
      </pub-date>
      <volume>3</volume>
      <issue>12</issue>
      <fpage>765</fpage>
      <lpage>770</lpage>
      <permissions>
        <copyright-statement>This article is copyright of Popeye Publishing, 2009</copyright-statement>
        <copyright-year>2009</copyright-year>
        <license license-type="open-access" href="http://creativecommons.org/licenses/by/4.0/">
          <license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.</license-p>
        </license>
      </permissions>
      <abstract>
        <p>Endodontic treatment is vital for preserving teeth as it involves removing pulp tissue and sealing the root canal system. Individuals with compromised function may present with aggressive forms of periapical lesions, which can complicate treatment approaches. Strict infection control measures are crucial during procedures for immunocompromised patients due to the increased risk of infections. This review discusses the connection between diseases and endodontic treatment outcomes. It sheds light on how conditions like diabetes, cardiovascular diseases, immunocompromised states, and osteoporosis can affect manifestations and management strategies. The clinical landscape presents challenges, such as delayed healing and persistent lesions in diabetes due to compromised responses to tissue repair issues caused by vascular changes in cardiovascular diseases, atypical periapical lesions in immunocompromised states, and compromised bone healing in osteoporosis. Managing these conditions requires an approach that puts the patient at the center. It involves monitoring, infection control measures, collaborating with specialists, and making decisions together with the patient. These insights emphasize the importance of endodontic practitioners considering health factors when planning treatments to achieve outcomes.&#13;
</p>
      </abstract>
      <kwd-group>
        <kwd>Systemic Diseases</kwd>
        <kwd> Endodontic Treatment</kwd>
        <kwd> Diabetes Mellitus</kwd>
        <kwd> Cardiovascular Diseases</kwd>
        <kwd> Immunocompromised States</kwd>
      </kwd-group>
    </article-meta>
  </front>
</article>