<?xml version="1.0" encoding="UTF-8" standalone="yes"?> <!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.2d1 20170631//EN" "JATS-journalpublishing1.dtd"> <article xlink="http://www.w3.org/1999/xlink" dtd-version="1.0" article-type="dentistry" lang="en"> <front> <journal-meta> <journal-id journal-id-type="publisher">JOHS</journal-id> <journal-id journal-id-type="nlm-ta">Journ of Health Scien</journal-id> <journal-title-group> <journal-title>Journal of HealthCare Sciences</journal-title> <abbrev-journal-title abbrev-type="pubmed">Journ of Health Scien</abbrev-journal-title> </journal-title-group> <issn pub-type="ppub">2231-2196</issn> <issn pub-type="opub">0975-5241</issn> <publisher> <publisher-name>Radiance Research Academy</publisher-name> </publisher> </journal-meta> <article-meta> <article-id pub-id-type="publisher-id">244</article-id> <article-id pub-id-type="doi">http://dx.doi.org/10.52533/JOHS.2023.31228</article-id> <article-id pub-id-type="doi-url"/> <article-categories> <subj-group subj-group-type="heading"> <subject>Dentistry</subject> </subj-group> </article-categories> <title-group> <article-title>The Impact of Saliva and Oral Microbiome on Restorative Dental Materials </article-title> </title-group> <contrib-group> <contrib contrib-type="author"> <name> <surname>Alakkad</surname> <given-names>Tarik</given-names> </name> </contrib> <contrib contrib-type="author"> <name> <surname>Fergani</surname> <given-names>Omar</given-names> </name> </contrib> <contrib contrib-type="author"> <name> <surname>Abulhamail</surname> <given-names>Lolwa</given-names> </name> </contrib> <contrib contrib-type="author"> <name> <surname>Tajuddin</surname> <given-names>Abdullah</given-names> </name> </contrib> <contrib contrib-type="author"> <name> <surname>Ashy</surname> <given-names>Yara</given-names> </name> </contrib> <contrib contrib-type="author"> <name> <surname>Munshi</surname> <given-names>Lulu</given-names> </name> </contrib> <contrib contrib-type="author"> <name> <surname>Aljehani</surname> <given-names>Fatmah</given-names> </name> </contrib> <contrib contrib-type="author"> <name> <surname>Bokhari</surname> <given-names>Ghazal</given-names> </name> </contrib> <contrib contrib-type="author"> <name> <surname>Sabir</surname> <given-names>Ghalia</given-names> </name> </contrib> </contrib-group> <pub-date pub-type="ppub"> <day>30</day> <month>11</month> <year>-0001</year> </pub-date> <volume>3</volume> <issue>12</issue> <fpage>752</fpage> <lpage>757</lpage> <permissions> <copyright-statement>This article is copyright of Popeye Publishing, 2009</copyright-statement> <copyright-year>2009</copyright-year> <license license-type="open-access" href="http://creativecommons.org/licenses/by/4.0/"> <license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.</license-p> </license> </permissions> <abstract> <p>Saliva and the oral microbiome play critical roles in the performance and longevity of dental restorative materials. Saliva__ampersandsign#39;s buffering capacity, pH regulation, and remineralization impact the durability and stability of materials. Variations in saliva composition among individuals can influence wear resistance and surface degradation of these materials. This review explores the intricate relationship between saliva, the oral microbiome, and restorative dental materials, emphasizing their mutual influences and the implications for dental practice. The oral microbiome, consisting of diverse microorganisms, further complicates this interaction. Bacterial adhesion, biofilm formation, and microbial metabolism significantly affect the integrity of restorative materials. For example, the degradation of composite resins by oral bacteria and their acidic byproducts can compromise the mechanical properties of these materials. Clinical manifestations of these interactions include deterioration of composite resin restorations, biofilm formation, and corrosion of amalgam restorations. Recognizing these manifestations is crucial for dentists to implement timely interventions and personalized management strategies. Regular monitoring and timely intervention, coupled with advancements in biomaterials, are key to enhancing the durability and effectiveness of restorative dental treatments. </p> </abstract> <kwd-group> <kwd>Restorative dental materials</kwd> <kwd> Oral microbiome</kwd> <kwd> Saliva</kwd> <kwd> Clinical manifestations</kwd> <kwd> Biomaterials in dentistry</kwd> </kwd-group> </article-meta> </front> </article>